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April 19, 2008

Brain Size and Alzheimer's

Though the cause of Alzheimer's disease (AD) remains unclear, research has indicated an association between AD and accumulations of amyloid-beta plaque and neurofibrillary tangles in the brain. While these abnormal brain changes have been viewed as a defining characteristic of AD, autopsies have shown that plaques and tangles can also be present in the brains of people who did not experience cognitive decline while alive. New research from the Oregon Health and Science University in Portland indicates that brain size may be involved in this discrepancy. The study, which was presented this week at the annual meeting of the American Academy of Neurology in Chicago, found that individuals with a large hippocampus were less likely to have symptoms of AD although plaques and tangles were present in their brains.
From: Study Links Brain Size to Alzheimer's

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Match It For Pratchett

  • What's This All About Then?
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